Toxicological Assessment of Methanolic Stem Bark and Leaf Extracts of Entada africana Guill. and Perr., Mimosaceae
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چکیده
منابع مشابه
Active chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damage
BACKGROUND Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) are traditionally used in Bamun (a western tribe of Cameroon) traditional medicine for the treatment of liver related diseases. In this study, the synergistic hepatoprotective effect of respective active fractions of the plants were investigated against paracetamol-induced toxicity in primary cultures of rat hepatocytes. ...
متن کاملThe Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis
Entada africana (Mimosaceae) was reported to have analgesic and antioxidant properties. The present study is aimed at investigating the effects of the root aqueous extract of Entada africana (EA) on an experimental model of endometriosis. The study was performed in rats orally treated with EA at doses of 127.5, 255, and 510 mg/kg. Microgynon® 30 served as the reference substance. Estradiol vale...
متن کاملEffects of Aqueous Root Bark Extracts of Anogeissus leiocarpus (DC) Guill & Perr and Terminalia avicennioides Guill & Perr on Redox and Haematological Parameters of Diethylnitrosamine-Administered Rats
Background: This study investigated the protective effects of aqueous extracts of Anogeissus leiocarpus (DC) Guill & Perr (Combretaceae) and Terminalia avicennioides Guill & Perr (Combretaceae) root barks, as well as their 1:1 (w/w) mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. Methods: Rats were orally administered distilled water, diethylnitrosami...
متن کاملEffects of methanolic leaf, bark and fruit extracts of Kigelia africana on haematology and erythrocyte membrane stability in rats
The toxicity, haematological and erythrocyte membrane stabilizing effects of different parts of Kigelia africana were evaluated. The different parts namely bark, leaf and fruit were subjected to phytochemical tests and flavonoids, saponnins, phlobatannin and tannins were found. Sub-acute toxicity study showed no adverse effect on erythrocytic indices at the doses tested for 28 days, Kigelia afr...
متن کاملeffects of aqueous root bark extracts of anogeissus leiocarpus (dc) guill & perr and terminalia avicennioides guill & perr on redox and haematological parameters of diethylnitrosamine-administered rats
background: this study investigated the protective effects of aqueous extracts of anogeissus leiocarpus (dc) guill & perr (combretaceae) and terminalia avicennioides guill & perr (combretaceae) root barks, as well as their 1:1 (w/w) mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. methods: rats were orally administered distilled water, diethylnitrosamine ...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2007
ISSN: 1811-7775
DOI: 10.3923/ijp.2007.393.399